Search results for "redox balance"

showing 7 items of 7 documents

A multiphase multiobjective dynamic genome-scale model shows different redox balancing among yeast species of the saccharomyces genus in fermentation

2021

Yeasts constitute over 1,500 species with great potential for biotechnology. Still, the yeast Saccharomyces cerevisiae dominates industrial applications, and many alternative physiological capabilities of lesser-known yeasts are not being fully exploited. While comparative genomics receives substantial attention, little is known about yeasts’ metabolic specificity in batch cultures. Here, we propose a multiphase multiobjective dynamic genome-scale model of yeast batch cultures that describes the uptake of carbon and nitrogen sources and the production of primary and secondary metabolites. The model integrates a specific metabolic reconstruction, based on the consensus Yeast8, and a kinetic …

Cryotolerant speciesPhysiologySaccharomyces cerevisiaeBatch fermentationsSaccharomyces speciesBiochemistryRedoxSaccharomycesMicrobiologyRedox balance03 medical and health sciencesSaccharomycesDynamic genome-scale modelsGeneticsMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biologyComparative genomics0303 health sciencesbiologyKinetic model030306 microbiologyChemistryKinetic modelbiology.organism_classificationYeastQR1-502YeastComputer Science ApplicationsFlux balance analysisMetabolismModeling and SimulationFermentationBiochemical engineeringBatch cultures
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Plasma redox response of Sicilian Opuntia Ficus Indica juice in young physically active women.

2017

It is known amateur female athletes show an altered redox status [1] and the consumption of Opuntia Ficus Indica (OFI) decreases oxidative stress (OS) in healthy humans [2]. Therefore, the aim of this study was to investigate whether the supplementation with Sicilian OFI juice affected plasma redox balance following a maximal effort test in young physically active women
 . This study was randomized, double blind, placebo controlled and crossover design. Eight women (23.25±2.95 years old, weight of 54.13±9.05 kg, height of 157.75±0.66 cm and BMI of 21.69±0.66 kg/m2) were randomly divided into 2 groups and each group was supplied with either 50 ml OFI, diluted to 170 ml with water, or 170 ml …

redox balanceSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' Sportiveoxidative stressindicaxanthinSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieAntioxidant supplementationAntioxidant supplementation; oxidative stress; redox balance; indicaxanthin
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Redox and autonomic responses to acute exercise-post recovery following Opuntia ficus-indica juice intake in physically active women

2021

Background: The aim of this study was to investigate if the supplementation with Opuntia ficus-indica (OFI) juice may affect plasma redox balance and heart rate variability (HRV) parameters following a maximal effort test, in young physically active women. Methods: A randomized, double blind, placebo controlled and crossover study comprising eight women (23.25 ± 2.95 years, 54.13 ± 9.05 kg, 157.75 ± 0.66 cm and BMI of 21.69 ± 0.66 kg/m2) was carried out. A juice containing OFI diluted in water and a Placebo solution were supplied (170 ml; OFI = 50 ml of OFI juice + 120 ml of water; Placebo = 170 ml beverage without Vitamin C and indicaxanthin). Participants consumed the OFI juice or Placebo…

Adult0301 basic medicineCactus pear juice supplementationOpuntia ficusTotal antioxidant capacityClinical nutritionmedicine.disease_causePlaceboYoung Adult03 medical and health scienceschemistry.chemical_compoundRedox balanceOxygen Consumption0302 clinical medicineAnimal scienceDouble-Blind MethodHigh frequencyHeart RatemedicineHumansHeart rate variabilityAutonomic nervous systemExerciseCross-Over StudiesNutrition and DieteticsSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' SportiveVitamin Cbusiness.industryOpuntiaHydrogen Peroxide030229 sport sciencesCrossover studyFruit and Vegetable JuicesHydroperoxideHydroperoxides030104 developmental biologychemistryOxidative stressOxidative streFemalebusinessLow frequencyOxidation-ReductionIndicaxanthinSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' MotorieOxidative stressResearch ArticleFood Science
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Metabolic Engineering of Bacterial Respiration: High vs. Low P/O and the Case of Zymomonas mobilis

2019

Respiratory chain plays a pivotal role in the energy and redox balance of aerobic bacteria. By engineering respiration, it is possible to alter the efficiency of energy generation and intracellular redox state, and thus affect the key bioprocess parameters: cell yield, productivity and stress resistance. Here we summarize the current metabolic engineering and synthetic biology approaches to bacterial respiratory metabolism, with a special focus on the respiratory chain of the ethanologenic bacterium Zymomonas mobilis. Electron transport in Z. mobilis can serve as a model system of bacterial respiration with low oxidative phosphorylation efficiency. Its application for redox balancing and re…

0301 basic medicineHistologyAerobic bacterialcsh:Biotechnologyrespiratory chainBiomedical EngineeringRespiratory chainBioengineering02 engineering and technologyOxidative phosphorylationZymomonas mobilisMetabolic engineeringredox balance03 medical and health scienceslcsh:TP248.13-248.65RespirationBioprocessstress resistencebiologyenergy couplingChemistryZymomonas mobilis021001 nanoscience & nanotechnologybiology.organism_classificationElectron transport chain030104 developmental biologyBiochemistry0210 nano-technologymetabolic engineeringBiotechnologyFrontiers in Bioengineering and Biotechnology
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Oxidative Status of Goats with Different CSN1S1 Genotypes Fed ad Libitum with Fresh and Dry Forages

2020

Forty late-lactation Girgentana goats were used to study the effect of diets fed ad libitum and &alpha

Settore AGR/19 - Zootecnica Speciale040301 veterinary sciencesPhysiologyClinical BiochemistryOxidative phosphorylationBiologymedicine.disease_causeBiochemistryredox balance0403 veterinary scienceSuperoxide dismutasechemistry.chemical_compoundNEFAAnimal sciencemedicinefresh forageMolecular Biologychemistry.chemical_classificationenzymatic antioxidantsCholesterolenzymatic antioxidantGlutathione peroxidaselcsh:RM1-950digestive oral and skin physiologygoat0402 animal and dairy scienceAlbumin04 agricultural and veterinary sciencesCell Biology040201 dairy & animal sciencelcsh:Therapeutics. PharmacologychemistryPolyphenolCSN1S1 genotypegoat; diet; fresh forage; redox balance; enzymatic antioxidantsbiology.proteinCSN1S1 genotype; diet; enzymatic antioxidants; fresh forage; goat; redox balancedietOxidative stressAntioxidants
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Selenium: A Cure for Autoimmune Thyroiditis.

2021

Autoimmune thyroiditis (AT) is a disease whose incidence has increased dramatically over the past few decades. In iodine sufficient areas, this pathological condition affects up to 5% of the general population. The higher incidence of AT observed in areas of the world with low-selenium (Se) soils apperas to be the consequence of a reduced activity of the intracellular Sedependent glutathione peroxidase activity. Se is involved, through selenoproteins, in the regulation of intracellular antioxidant, redox and anti-inflammatory processes. As a component of selenoproteins, Se exerts various structural and enzymatic functions. A low Se/high fat diet can cause selenoprotein changes and promote t…

business.industryEndocrinology Diabetes and MetabolismThyroiditis Autoimmunechemistry.chemical_elementHashimoto Diseasemedicine.diseaseIodide PeroxidaseAutoimmune thyroiditisSeleniumchemistryImmunologyImmunology and AllergyMedicineHumansSettore MED/49 - Scienze Tecniche Dietetiche ApplicatebusinessSelenium autoimmune thyroiditis redox balanceSeleniumEndocrine, metabolicimmune disorders drug targets
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Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation

2018

Abstract Aims Aircraft noise causes endothelial dysfunction, oxidative stress, and inflammation. Transportation noise increases the incidence of coronary artery disease, hypertension, and stroke. The underlying mechanisms are not well understood. Herein, we investigated effects of phagocyte-type NADPH oxidase (Nox2) knockout and different noise protocols (around-the-clock, sleep/awake phase noise) on vascular and cerebral complications in mice. Methods and results C57BL/6j and Nox2 −/− (gp91phox −/−) mice were exposed to aircraft noise (maximum sound level of 85 dB(A), average sound pressure level of 72 dB(A)) around-the-clock or during sleep/awake phases for 1, 2, and 4 days. Adverse effec…

0301 basic medicinemedicine.medical_specialtyEndotheliumAircraft10208 Institute of NeuropathologyInflammation610 Medicine & health030204 cardiovascular system & hematologySystemic inflammationmedicine.disease_cause2705 Cardiology and Cardiovascular Medicine03 medical and health sciences0302 clinical medicineBasic ScienceVascular BiologyInternal medicineeNOS uncouplingmedicineHumansEndothelial dysfunctionEndothelial dysfunctionInflammationSystemic inflammationbusiness.industryEnvironmental stressorCerebral redox balancemedicine.diseaseEnvironmental stressorSleep deprivationNoiseSleep deprivationOxidative Stress030104 developmental biologymedicine.anatomical_structureEndocrinologyNADPH oxidase-derived oxidative stress570 Life sciences; biologymedicine.symptombusinessNoiseCardiology and Cardiovascular MedicineOxidative stressNoise exposure
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